Use Modafinil (Provigil) just as directed over the label, or as prescribed by your medical professional. Do not use in greater or smaller sized amounts or for more time than proposed.
C: Use with warning if Added benefits outweigh challenges. Animal reports display possibility and human experiments not out there or neither animal nor human scientific tests performed.
Even though modafinil is mostly viewed as both of those safe and well-tolerated, it’s a robust compound that will cause some unfavorable Unwanted side effects, which might range from small annoyances to important health threats.
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Det mistenkes at modafinil gir medfødte misdannelser hos barnet ved bruk less than graviditet. Snakk med legen din om de prevensjonsmetoder som vil være best for deg mens du tar Modiodal (og i to måneder etter at du slutter), eller hvis du har andre bekymringer. Kjøring og bruk av maskiner Modiodal kan forårsake tåkesyn eller svimmelhet hos opptil 1 av 10 personer.
iloperidone increases levels of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Iloperidone is a time-dependent CYP3A inhibitor and will result in increased plasma amounts of medications predominantly eliminated by CYP3A4.
You might need to website take a decrease dose of modafinil When your liver is just not Doing work at the same time correctly. If there is a concern concerning the wellness within your liver, your Health care supplier could do exams to determine how well it is actually Doing the job.
Derimot kan enkelte grader av narkolepsi gi begrensninger med tanke på førerrett. Det er legen som vurderer om din medisinbruk og ditt sykdomsbilde utgjør en trafikksikkerhetsrisiko eller ikke.
nelfinavir will boost the degree or result of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
fedratinib will enhance the stage or result of modafinil by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Observe. Change dose of medicines which are CYP2C19 substrates as essential.
Legemiddelgruppe som hemmer enzymet hydroksymetylglutarylkoenzym A (HMG-CoA) i leveren og i andre vev. HMG-CoA er et enzym i tidlig fase av kolesterolsyntesen. Enzymet katalyserer og er hastighetsbegrensende i dannelse av forstadier til kolesterol og en rekke andre biologisk viktige substanser.
Saletu and colleagues published two papers examining EEG variances in narcoleptics and regular controls and the effects of modafinil on nearby EEG distinctions of narcoleptics within a double-blind, placebo-controlled, crossover demo. Both equally scientific studies as opposed EEG spectral energy distinctions for 16 narcoleptics and sixteen usual controls in resting EEG. The 2nd Element of both research involved placing the narcoleptic individuals within a double-blind, placebo-controlled, crossover examine of modafinil consisting of two remedy intervals Every single of 3 weeks separated by a 1-week washout phase and a measurement of EEG activity at the beginning and end of each cure period.
Keep away from or substitute Yet another drug for these medications when probable. Appraise for loss of therapeutic effect if medication need to be coadministered.
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